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DMNP-EDTA

Catalog No. T31552 CAS 117367-86-9

Synonyms: DMNPEDTA, DM-Nitrophen, DM Nitrophen, DMNP EDTA

DMNP-EDTA is a caged Ca2+ chelator which photouncages Cu2+ ions for light-controlled gene expression in yeast.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

DMNP-EDTA, CAS 117367-86-9

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

DMNP-EDTA is a caged Ca2+ chelator which photouncages Cu2+ ions for light-controlled gene expression in yeast.

Synonyms	DMNPEDTA, DM-Nitrophen, DM Nitrophen, DMNP EDTA
Molecular Weight	473.39
Formula	C18H23N3O12
CAS No.	117367-86-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Kusen PM, Wandrey G, Krewald V, Holz M, Berstenhorst SMZ, Büchs J, Pietruszka J. Light-controlled gene expression in yeast using photocaged Cu(2). J Biotechnol. 2017 Sep 20;258:117-125. doi: 10.1016/j.jbiotec.2017.04.032. Epub 2017 Apr 25. PubMed PMID: 28455204. 2. Wang M, Chen Z, Xing Y, Zhang X, Dong XZ, Ji GJ. Localized Ca2+ uncaging induces Ca2+ release through IP3R in smooth muscle. Acta Pharmacol Sin. 2006 Jul;27(7):939-44. PubMed PMID: 16787580. 3. Ji G, Feldman M, Doran R, Zipfel W, Kotlikoff MI. Ca2+ -induced Ca2+ release through localized Ca2+ uncaging in smooth muscle. J Gen Physiol. 2006 Mar;127(3):225-35. PubMed PMID: 16505145; PubMed Central PMCID: PMC2151500. 4. Ullrich ND, Voets T, Prenen J, Vennekens R, Talavera K, Droogmans G, Nilius B. Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice. Cell Calcium. 2005 Mar;37(3):267-78. PubMed PMID: 15670874.

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

DMNP-EDTA 117367-86-9 DMNPEDTA DM-Nitrophen DM Nitrophen DMNP EDTA inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.