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DA-7867

Catalog No. T23947 CAS 380382-38-7

Synonyms: UNII-491MT9GU8K, DA 7867, DA7867

DA-7867 is a novel oxazolidinone. DA-7867 had the lowest MIC for 90% of the aerobic gram-positive bacterial strains tested (≤0.25 μg/ml) and it was more potent than linezolid. DA-7867 was the most active drug with a MIC(90) of 0.125 μg/ml.

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DA-7867, CAS 380382-38-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,670.00
50 mg	6-8 weeks	$ 2,180.00
100 mg	6-8 weeks	$ 2,800.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	UNII-491MT9GU8K, DA 7867, DA7867
Molecular Weight	411.39
Formula	C19H18FN7O3
CAS No.	380382-38-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Vera-Cabrera L, Castro-Garza J, Rendon A, Ocampo-Candiani J, Welsh O, Choi SH, Blackwood K, Molina-Torres C. In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867. Antimicrob Agents Chemother. 2005 Oct;49(10):4351-3. PubMed PMID: 16189119; PubMed Central PMCID: PMC1251498. 2. Yong D, Yum JH, Lee K, Chong Y, Choi SH, Rhee JK. In vitro activities of DA-7867, a novel oxazolidinone, against recent clinical isolates of aerobic and anaerobic bacteria. Antimicrob Agents Chemother. 2004 Jan;48(1):352-7. Erratum in: Antimicrob Agents Chemother. 2004 May;48(5):1918. PubMed PMID: 14693566; PubMed Central PMCID: PMC310204. 3. Vera-Cabrera L, Brown-Elliott BA, Wallace RJ Jr, Ocampo-Candiani J, Welsh O, Choi SH, Molina-Torres CA. In vitro activities of the novel oxazolidinones DA-7867 and DA-7157 against rapidly and slowly growing mycobacteria. Antimicrob Agents Chemother. 2006 Dec;50(12):4027-9. Epub 2006 Oct 2. PubMed PMID: 17015632; PubMed Central PMCID: PMC1693997. 4. Vera-Cabrera L, Daw-Garza A, Said-Fernández S, Lozano-Garza HG, de Torres NW, Rocha NC, Ocampo-Candiani J, Choi SH, Welsh O. Therapeutic effect of a novel oxazolidinone, DA-7867, in BALB/c mice infected with Nocardia brasiliensis. PLoS Negl Trop Dis. 2008 Sep 10;2(9):e289. doi: 10.1371/journal.pntd.0000289. PubMed PMID: 18820738; PubMed Central PMCID: PMC2553479.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

DA-7867 380382-38-7 UNII-491MT9GU8K DA 7867 DA7867 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.