Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cyclo(Tyr-Gly) is a natural product for research related to life sciences. The catalog number is TN6687 and the CAS number is 5625-49-0.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | Inquiry | $ 730.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 500.00 |
Description | Cyclo(Tyr-Gly) is a natural product for research related to life sciences. The catalog number is TN6687 and the CAS number is 5625-49-0. |
In vitro | METHODS AND RESULTS: Enrichment culture of soil samples with cyclo(Gly-Gly) and cyclo(Gly-l-Tyr) as a carbon and/or a nitrogen source resulted in the isolation of Arthrobacter sp. 1-3-1 and the coryneform rod bacterium, strain T-1-3-Y, as the bacteria which most highly assimilated cyclo(Gly-Gly) and cyclo(Gly-l-Tyr), respectively. Both bacteria had the enzyme activity hydrolyzing DKPs intracellularly in contrast to the extracellular cyclo(Gly-Gly) hydrolase reported previously. The cells of Arthrobacter sp. 1-3-1 degraded all diketopiperazines tested, including cyclo(Gly-Gly), cyclo(Gly-l-Ala), cyclo(Gly-l-Val), cyclo(Gly-l-Leu), cyclo(Gly-l-Ile), cyclo(Gly-l-Met), cyclo(Gly-l-Phe), cyclo(Gly-l-Tyr)(Cyclo(Tyr-Gly)), cyclo(l-Ala-l-Tyr), cyclo(l-Val-l-Tyr), cyclo(l-Leu-l-Tyr), cyclo(l-Tyr-l-Tyr), cyclo(l-Phe-l-Leu), cyclo(Gly-d-Ala), and cyclo(Gly-d-Leu). On the other hand, the degradation of d-amino acid-containing DKPs or cyclo(Gly-Gly) by the cells of the strain T-1-3-Y were detected hardly or not at all, respectively. CONCLUSIONS: From the result that DKP hydrolase in the strain T-1-3-Y had a higher stereospecificity than that in Arthrobacter sp. 1-3-1, the diversity of DKP hydrolases were found to be in nature. |
Molecular Weight | 220.22 |
Formula | C11H12N2O3 |
CAS No. | 5625-49-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Cyclo(Tyr-Gly) 5625-49-0 Cyclo(TyrGly) Cyclo(Tyr Gly) inhibitor inhibit