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Cucurbitacin IIA

Cucurbitacin IIA
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
Catalog No. T3S1471Cas No. 58546-34-2
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Purity:99.87%
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Cucurbitacin IIA

Catalog No. T3S1471Cas No. 58546-34-2
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$64In Stock
10 mg$113In Stock
25 mg$213In Stock
50 mg$319In Stock
100 mg$475In Stock
500 mg$987In Stock
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Product Introduction

Bioactivity
Description
1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3.
AliasDihydrocucurbitacin Q1, Hemslecin A, Curcurbitacin IIA
Chemical Properties
Molecular Weight562.73
FormulaC32H50O8
Cas No.58546-34-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
DMSO: 91 mg/mL (161.7 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7771 mL8.8853 mL17.7705 mL88.8526 mL
5 mM0.3554 mL1.7771 mL3.5541 mL17.7705 mL
10 mM0.1777 mL0.8885 mL1.7771 mL8.8853 mL
20 mM0.0889 mL0.4443 mL0.8885 mL4.4426 mL
50 mM0.0355 mL0.1777 mL0.3554 mL1.7771 mL
100 mM0.0178 mL0.0889 mL0.1777 mL0.8885 mL

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