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Corynanthine

Catalog No. T19910 CAS 483-10-3

Synonyms: NSC-407306, NSC407306, NSC 407306

Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.

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Corynanthine, CAS 483-10-3

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.

Synonyms	NSC-407306, NSC407306, NSC 407306
Molecular Weight	354.44
Formula	C21H26N2O3
CAS No.	483-10-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Franco-Belussi L, De Oliveira C, Sköld HN. Regulation of eye and jaw colouration in three-spined stickleback Gasterosteus aculeatus. J Fish Biol. 2018 Mar 25. doi: 10.1111/jfb.13620. [Epub ahead of print] PubMed PMID: 29577284. 2. Cippitelli A, Brunori G, Schoch J, Armishaw CJ, Wu J, Zaveri NT, Giulianotti MA, Welmaker GS, Toll L. Differential regulation of alcohol taking and seeking by antagonism at α4β2 and α3β4 nAChRs. Psychopharmacology (Berl). 2018 Mar 23. doi: 10.1007/s00213-018-4883-y. [Epub ahead of print] PubMed PMID: 29572652. 3. Kotagale NR, Ali MT, Chopde CT, Umekar MJ, Taksande BG. Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α(2)-adrenoceptors. Pharmacol Biochem Behav. 2018 Apr;167:42-49. doi: 10.1016/j.pbb.2018.03.002. Epub 2018 Mar 10. PubMed PMID: 29530492. 4. Samur DN, Arslan R, Aydın S, Bektas N. Valnoctamide: The effect on relieving of neuropathic pain and possible mechanisms. Eur J Pharmacol. 2018 May 15;827:208-214. doi: 10.1016/j.ejphar.2018.03.006. Epub 2018 Mar 6. PubMed PMID: 29522726.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Corynanthine 483-10-3 NSC-407306 NSC407306 NSC 407306 inhibitor inhibit

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