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Collagenase inhibitor CI-2

Catalog No. T23906 CAS 101470-42-2

Synonyms: SC 40827

SC 40827 is a Collagenase inhibitor CI-2.

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Collagenase inhibitor CI-2 Chemical Structure

Collagenase inhibitor CI-2, CAS 101470-42-2

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

SC 40827 is a Collagenase inhibitor CI-2.

Synonyms	SC 40827
Molecular Weight	540.661
Formula	C29H40N4O6
CAS No.	101470-42-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Lahdentausta L, Leskelä J, Winkelmann A, Tervahartiala T, Sorsa T, Pesonen E, Pussinen PJ. Serum MMP-9 Diagnostics, Prognostics, and Activation in Acute Coronary Syndrome and Its Recurrence. J Cardiovasc Transl Res. 2018 Jan 18. doi: 10.1007/s12265-018-9789-x. [Epub ahead of print] PubMed PMID: 29349668. 2. Wills B, Cardona AF, Rojas L, Ruiz-Patiño A, Arrieta O, Reguart N, Carranza H, Vargas C, Otero J, Corrales L, Martín C, Cuello M, Pino LE, Rolfo C, Rosell R, Zatarain-Barrón ZL; Latin-American Consortium for the Investigation of Lung Cancer (CLICaP). Survival Outcomes According to TIMP1 and EGFR Expression in Heavily Treated Patients with Advanced Non-small Cell Lung Cancer who Received Biweekly Irinotecan Plus Bevacizumab. Anticancer Res. 2017 Nov;37(11):6429-6436. PubMed PMID: 29061829. 3. Mechmeche R, Zaroui A, Aloui S, Boukhris M, Allal-Elasmi M, Kaabachi N, Zouari B. Late mitral restenosis after percutaneous commissurotomy: Predictive value of inflammation and extracellular matrix remodeling biomarkers. Heart Lung. 2017 Jul - Aug;46(4):258-264. doi: 10.1016/j.hrtlng.2017.03.006. Epub 2017 Apr 24. PubMed PMID: 28450150. 4. Martines A, Stifanese R, Faelli EL, Perasso L, Melloni I, Ruggeri P, Averna M. Calpain-1 resident in lipid raft/caveolin-1 membrane microdomains plays a protective role in endothelial cells. Biochimie. 2017 Feb;133:20-27. doi: 10.1016/j.biochi.2016.12.002. Epub 2016 Dec 9. PubMed PMID: 27956030.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Collagenase inhibitor CI-2 101470-42-2 SC 40827 Collagenase inhibitor CI 2 SC40827 SC-40827 Collagenase inhibitor CI2 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.