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Cefepime dihydrochloride

Catalog No. T20897 CAS 107648-80-6

Synonyms: Cefepime hydrochloride anhydrous, BMY-28142 dihydrochloride, Cepimax, Axepim, Cefepime HCl

Cefepime dihydrochloride, a broad-spectrum fourth-generation cephalosporin, binds and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Cefepime dihydrochloride Chemical Structure

Cefepime dihydrochloride, CAS 107648-80-6

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Cefepime dihydrochloride, a broad-spectrum fourth-generation cephalosporin, binds and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall.

Synonyms	Cefepime hydrochloride anhydrous, BMY-28142 dihydrochloride, Cepimax, Axepim, Cefepime HCl
Molecular Weight	553.48
Formula	C19H26Cl2N6O5S2
CAS No.	107648-80-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

References and Literature

1. Jagadeesh Kumar V, Badarinadh Gupta P, Pavan Kumar KS, Prasada Rao KV, Rao KR, Prasanna SJ, Kumar Sharma H, Mukkanti K. Identification and characterization of new degradation products of cefepime dihydrochloride monohydrate drug substance during stress stability studies. Anal Sci. 2010;26(10):1081-6. PubMed PMID: 20953052. 2. Jiang X, Zhang Z, Li M, Zhou D, Ruan F, Lu Y. Detection of extended-spectrum beta-lactamases in clinical isolates of Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2006 Sep;50(9):2990-5. PubMed PMID: 16940093; PubMed Central PMCID: PMC1563526. 3. Zhao L, Guo JF, Zhang AJ, Zhao YM. [Rapid identification of the isomeric impurity in raw drug of cefepime dihydrochloride by liquid chromatography-tandem mass spectrometry]. Yao Xue Xue Bao. 2005 Apr;40(4):361-4. Chinese. PubMed PMID: 16011268. 4. Musiał W, Zajac M. Stability of cefepime dihydrochloride monohydrate in solid state. Acta Pol Pharm. 2002 Jul-Aug;59(4):243-6. PubMed PMID: 12403297.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Cefepime dihydrochloride 107648-80-6 Cefepime Dihydrochloride BMY28142 BMY28142 Dihydrochloride Cefepime hydrochloride anhydrous BMY-28142 BMY 28142 Dihydrochloride BMY-28142 Dihydrochloride Cefepime BMY-28142 dihydrochloride Cepimax Axepim Cefepime HCl BMY 28142 inhibitor inhibit

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