Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50= 0.06 μM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 μM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50= ~100 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 123.00 | |
5 mg | 35 days | $ 540.00 | |
10 mg | 35 days | $ 890.00 |
Description | CXCR3 antagonist 6c is an antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3).1It inhibits calcium mobilization induced by chemokine (C-X-C motif) ligand 11 (CXCL11) in HEK293 cells expressing the human receptor (IC50= 0.06 μM). It is selective for CXCR3 over a panel of 14 human G protein-coupled receptors at 10 μM. CXCR3 antagonist 6c inhibits CXCR3-mediated migration of isolated human T cells (IC50= ~100 nM). |
Molecular Weight | 616.97 |
Formula | C30H32Cl3N5O3 |
CAS No. | 870998-13-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: >100 mM
You can also refer to dose conversion for different animals. More
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CXCR3 Antagonist 6c 870998-13-3 CXCR-3 Antagonist 6c inhibitor inhibit