Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 75.00 | |
10 mg | 35 days | $ 143.00 | |
25 mg | 35 days | $ 335.00 | |
50 mg | 35 days | $ 558.00 |
Description | Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 μM. |
Molecular Weight | 325.36 |
Formula | C19H19NO4 |
CAS No. | 615264-52-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 20 mg/mL
DMSO:PBS (pH 7.2)(1:5): 0.5 mg/mL
DMSO: 30 mg/mL
DMF: 30 mg/mL
You can also refer to dose conversion for different animals. More
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CAY10486 615264-52-3 CAY 10486 CAY-10486 inhibitor inhibit