Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome C release, or channel formation in phospholipid membranes in the absence of C16 ceramide.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 249.00 | |
5 mg | Inquiry | $ 675.00 |
Description | C16 dihydro Ceramide is a bioactive sphingolipid and precursor in the de novo synthesis of C16 ceramide (d18:0/16:0) that lacks the 4,5-trans double bond.[1] C16 dihydro Ceramide (0-46 nM) inhibits C16 ceramide-induced membrane permeabilization, measured as cytochrome C oxidation, in rat liver mitochondria in a concentration-dependent manner. It also inhibits C16 ceramide-induced channel formation in liposomes. C16 dihydro ceramide is biologically inactive as a single agent, lacking the ability to induce apoptosis, cytochrome C release, or channel formation in phospholipid membranes in the absence of C16 ceramide. |
Synonyms | Ceramide (d18:0/16:0), Cer(d18:0/16:0), N-hexadecanoyl-D-erythro-Dihydrosphingosine, N-Palmitoyl Sphinganine |
Molecular Weight | 539.93 |
Formula | C34H69NO3 |
CAS No. | 5966-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
Chloroform:Methanol (5:1): Soluble
Ethanol: Soluble
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C16 dihydro Ceramide (d18:0/16:0) 5966-29-0 Ceramide (d18:0/16:0) Cer(d18:0/16:0) d18:0/16:0 C-16 dihydro Ceramide (d18:0/16:0) C16 dihydro Ceramide Ceramide N-hexadecanoyl-D-erythro-Dihydrosphingosine N-Palmitoyl Sphinganine inhibitor inhibit