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Bromethalin

Catalog No. T30592 CAS 63333-35-7

Synonyms: EL-614, EL614, EL 614

Bromethalin works by uncoupling mitochondrial oxidative phosphorylation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Bromethalin, CAS 63333-35-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Bromethalin works by uncoupling mitochondrial oxidative phosphorylation.

Synonyms	EL-614, EL614, EL 614
Molecular Weight	577.93
Formula	C14H7Br3F3N3O4
CAS No.	63333-35-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Lehner A, Bokhart M, Johnson M, Buchweitz J. Characterization of Bromethalin and its Degradation Products in Veterinary Toxicology Samples by GC-MS-MS. J Anal Toxicol. 2018 Oct 11. doi: 10.1093/jat/bky072. [Epub ahead of print] PubMed PMID: 30307505. 2. DeClementi C, Sobczak BR. Common Rodenticide Toxicoses in Small Animals. Vet Clin North Am Small Anim Pract. 2018 Nov;48(6):1027-1038. doi: 10.1016/j.cvsm.2018.06.006. Epub 2018 Aug 31. Review. PubMed PMID: 30173927. 3. Walton KL, Otto CM. Retrospective evaluation of feline rodenticide exposure and gastrointestinal decontamination: 146 cases (2000-2010). J Vet Emerg Crit Care (San Antonio). 2018 Sep;28(5):457-463. doi: 10.1111/vec.12748. Epub 2018 Aug 21. PubMed PMID: 30129699. 4. Becker MD, Young BC. Treatment of severe lipophilic intoxications with intravenous lipid emulsion: a case series (2011-2014). Vet Med (Auckl). 2017 Oct 30;8:77-85. doi: 10.2147/VMRR.S129576. eCollection 2017. PubMed PMID: 30050859; PubMed Central PMCID: PMC6042488.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Bromethalin 63333-35-7 EL-614 EL614 EL 614 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.