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BRL 55834

Catalog No. T26905 CAS 131899-25-7

Synonyms: BRL55834, BRL-55834

BRL 55834, a potassium channel activator, has shown to relax airways and vasculature in vivo.

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BRL 55834, CAS 131899-25-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

BRL 55834, a potassium channel activator, has shown to relax airways and vasculature in vivo.

Synonyms	BRL55834, BRL-55834
Molecular Weight	393.35
Formula	C18H20F5NO3
CAS No.	131899-25-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bowring NE, Arch JR, Buckle DR, Taylor JF. Comparison of the airways relaxant and hypotensive potencies of the potassium channel activators BRL 55834 and levcromakalim (BRL 38227) in vivo in guinea-pigs and rats. Br J Pharmacol. 1993 Aug;109(4):1133-9. PubMed PMID: 8401925; PubMed Central PMCID: PMC2175747. 2. Arch JR, Bowring NE, Buckle DR. Evaluation of the novel potassium channel activator BRL 55834 as an inhaled bronchodilator in guinea-pigs and rats: comparison with levcromakalim and salbutamol. Pulm Pharmacol. 1994 Apr;7(2):121-8. PubMed PMID: 8081072. 3. Shi Z, Yan Z, Luo W. [Antigen-induced airway leakage in asthmatic guinea-pigs and the effects of BRL 55834]. Zhonghua Jie He He Hu Xi Za Zhi. 1998 Apr;21(4):229-32. Chinese. PubMed PMID: 11326971. 4. Shi Z, Luo W, Xiu Q, Ye Y, Yan Z, Zhu Q. Effects of BRL 55 834 on allergen-induced bronchoconstriction and airway inflammation in sensitized guinea pigs. Chin Med J (Engl). 1999 Nov;112(11):988-91. PubMed PMID: 11721481.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BRL 55834 131899-25-7 BRL55834 BRL-55834 inhibitor inhibit

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