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BN 52111

Catalog No. T26876 CAS 120889-14-7

Synonyms: BN-52111, BN52111

BN 52111 is a platelet activating factor antagonist.

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BN 52111, CAS 120889-14-7

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

Bulk Inquiry

This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

BN 52111 is a platelet activating factor antagonist.

Synonyms	BN-52111, BN52111
Molecular Weight	612.734
Formula	C33H58BrNO4
CAS No.	120889-14-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Braquet P, Hosford D, Koltz P, Guilbaud J, Paubert-Braquet M. Effect of platelet-activating factor on tumor necrosis factor-induced superoxide generation from human neutrophils. Possible involvement of G proteins. Lipids. 1991 Dec;26(12):1071-5. PubMed PMID: 1668107. 2. Paubert-Braquet M, Hosford D, Klotz P, Guilbaud J, Braquet P. Tumor necrosis factor alpha 'primes' the platelet-activating factor-induced superoxide production by human neutrophils: possible involvement of G proteins. J Lipid Mediat. 1990;2 Suppl:S1-4. PubMed PMID: 1966810. 3. Pons F, Touvay C, Lejeune V, Carré C, Vilain B, Broquet C, Mencia-Huerta JM, Braquet P. Action of platelet-activating factor (PAF) antagonists on the bronchopulmonary effects of PAF in the guinea-pig. J Lipid Mediat. 1989 Nov-Dec;1(6):329-40. PubMed PMID: 2519901. 4. Mandi Y, Farkas G, Koltai M, Beladi I, Mencia-Huerta JM, Braquet P. The effect of the platelet-activating factor antagonist, BN 52021, on human natural killer cell-mediated cytotoxicity. Immunology. 1989 Jul;67(3):370-4. PubMed PMID: 2759659; PubMed Central PMCID: PMC1385355.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BN 52111 120889-14-7 BN-52111 BN52111 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.