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BN 50739

Catalog No. T26875   CAS 128672-07-1
Synonyms: BN50739, BN-50739

BN 50739 is an antagonist of platelet-activating factor (PAF). BN 50739 suppresses certain cardiac arrhythmias. PAF is released from ischaemic myocardium and may contribute to initiation of ischaemia-induced ventricular fibrillation (VF)

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BN 50739 Chemical Structure
BN 50739, CAS 128672-07-1
Pack Size Availability Price/USD Quantity
25 mg 8-10 weeks $ 2,120.00
50 mg 8-10 weeks $ 2,780.00
100 mg 8-10 weeks $ 3,700.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description BN 50739 is an antagonist of platelet-activating factor (PAF). BN 50739 suppresses certain cardiac arrhythmias. PAF is released from ischaemic myocardium and may contribute to initiation of ischaemia-induced ventricular fibrillation (VF)
Synonyms BN50739, BN-50739
Molecular Weight 596.19
Formula C28H26ClN5O2S3
CAS No. 128672-07-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Baker KE, Curtis MJ. Protection against ventricular fibrillation by the PAF antagonist, BN-50739, involves an ischaemia-selective mechanism. J Cardiovasc Pharmacol. 1999 Sep;34(3):394-401. PubMed PMID: 10470998. 2. Kintner DB, Fitzpatrick JH Jr, Gilboe DD. Hyperglycemic damage to mitochondrial membranes during cerebral ischemia: amelioration by platelet-activating factor antagonist BN 50739. J Neurochem. 1997 Sep;69(3):1219-27. PubMed PMID: 9282946. 3. Sun D, Gilboe DD. Effect of the platelet-activating factor antagonist BN 50739 and its diluents on mitochondrial respiration and membrane lipids during and following cerebral ischemia. J Neurochem. 1994 May;62(5):1929-38. PubMed PMID: 8158141. 4. Ranaut K, Singh M. BN-50739: a PAF antagonist and limitation of myocardial infarct size. Methods Find Exp Clin Pharmacol. 1993 Jan-Feb;15(1):9-14. PubMed PMID: 8479250.

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Keywords

BN 50739 128672-07-1 BN50739 BN-50739 inhibitor inhibit

 

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