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BK 129

Catalog No. T26830 CAS 105919-73-1

Synonyms: BK-129, BK129

BK 129 is a local anesthetic with relaxant properties. BK 129 inhibits Ca2+ entry into the smooth muscle cell and Ca2+ release from sarcoplasmic reticulum.

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BK 129, CAS 105919-73-1

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,520.00
50 mg	6-8 weeks	$ 1,980.00
100 mg	6-8 weeks	$ 2,500.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

BK 129 is a local anesthetic with relaxant properties. BK 129 inhibits Ca2+ entry into the smooth muscle cell and Ca2+ release from sarcoplasmic reticulum.

Synonyms	BK-129, BK129
Molecular Weight	392.53
Formula	C22H36N2O4
CAS No.	105919-73-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Sotníková R. Effect of a new antiarrhythmic BK 129 on canine vascular smooth muscle in vitro. Methods Find Exp Clin Pharmacol. 1992 Apr;14(3):175-81. PubMed PMID: 1625501. 2. Gibala P, Sotníková R, Knezl V, Drímal J. Antiarrhythmic activity of the hydrochloride of 1-methoxymethyl-2-(1-perhydroazepinyl)ethyl ester of 2-(n)-pentyloxycarbanilic acid. Arzneimittelforschung. 1987 Feb;37(2):149-52. PubMed PMID: 3580018. 3. Gibala P, Sotníková R, Knezl V, Drímal J. Cardiac electrophysiologic actions of the hydrochloride of 1-methoxymethyl-2-(1-perhydroazepinyl)ethyl ester of 2-(n)-pentyloxycarbanilic acid in the anesthetized dog. Arzneimittelforschung. 1987 Mar;37(3):326-8. PubMed PMID: 3593445. 4. Stolc S. Inhibition of ion currents in membrane of sensory neuron by the antiarrhythmic drug BK 129 and selected Ca2+ entry blockers. Gen Physiol Biophys. 1993 Dec;12(6):517-31. Erratum in: Gen Physiol Biophys 1994 Aug;13(4):339. PubMed PMID: 8070644.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BK 129 105919-73-1 BK-129 BK129 inhibitor inhibit

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