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BIBP3226

Catalog No. T26801 CAS 159013-54-4

Synonyms: BIBP 3226, BIBP-3226

BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

BIBP3226, CAS 159013-54-4

Pack Size	Availability	Price/USD	Quantity
1 mg	35 days	$ 123.00
25 mg	35 days	$ 1,770.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

BIBP3226 is a potent and selective antagonist for the Neuropeptide Y receptor Y1 and the neuropeptide FF receptor.

Synonyms	BIBP 3226, BIBP-3226
Molecular Weight	473.57
Formula	C27H31N5O3
CAS No.	159013-54-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Fang Q, Guo J, He F, Peng YL, Chang M, Wang R. In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist. Peptides. 2006 Sep;27(9):2207-13. PubMed PMID: 16762456. 2. Engström M, Wurster S, Savola JM, Panula P. Functional properties of Pfr(Tic)amide and BIBP3226 at human neuropeptide FF2 receptors. Peptides. 2003 Dec;24(12):1947-54. PubMed PMID: 15127947. 3. Chen SH, Cheung RT. Intracerebroventricular injection of a neuropeptide Y-Y1 receptor agonist increases while BIBP3226, a Y1 antagonist, reduces the infarct volume following transient middle cerebral artery occlusion in rats. Neuroscience. 2003;116(1):119-26. PubMed PMID: 12535945. 4. Van Liefde, Vanderheyden PM, De Backer JP, Ebinger G, Vauquelin G. Effects of BIBP3226 and BIBP3435 on cytosolic calcium in neuropeptide Y Y1 receptor-transfected Chinese hamster ovary cells and wild type CHO-K1 cells. J Recept Signal Transduct Res. 2001 Feb;21(1):11-23. PubMed PMID: 11693170.

Dose Conversion

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

BIBP3226 159013-54-4 BIBP 3226 BIBP-3226 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.