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BD1063 dhydrochloride

BD1063 dhydrochloride
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Purity:99.33%
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BD1063 dhydrochloride

Catalog No. T7488Cas No. 206996-13-6
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
2 mg$41In Stock
5 mg$66In Stock
10 mg$92In Stock
25 mg$197In Stock
50 mg$357In Stock
100 mg$525In Stock
200 mg$739In Stock
500 mg$1,130In Stock
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Product Introduction

Bioactivity
Description
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
In vivo
BD 1063 dose-dependently reduced ethanol self-administration in sP rats (3.3–11 mg/kg) and withdrawn, dependent Wistar rats (4–11 mg/kg) at doses that did not modify mean ethanol self-administration in non-dependent Wistar controls[1]
Animal Research
Rats (controls, N=11;?dependent, N=9) were pretreated with BD-1063 (0, 4.4, 7 and 11 mg/kg of body weight, free base weights) using a within-subject Latin square design.?sP rats: Rats (N=9) were pretreated with BD-1063 (0, 3, 4.4, 7 and 11 mg/kg of body weight, free base basis) using a within-subject Latin square design[1].
AliasBD1063
Chemical Properties
Molecular Weight346.12
FormulaC13H20Cl4N2
Cas No.206996-13-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 50 mg/mL (144.46 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM2.8892 mL14.4459 mL28.8917 mL144.4586 mL
5 mM0.5778 mL2.8892 mL5.7783 mL28.8917 mL
10 mM0.2889 mL1.4446 mL2.8892 mL14.4459 mL
20 mM0.1445 mL0.7223 mL1.4446 mL7.2229 mL
50 mM0.0578 mL0.2889 mL0.5778 mL2.8892 mL
100 mM0.0289 mL0.1445 mL0.2889 mL1.4446 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg, each TargetMol | Animal experiments animal weighs 20 g, and the dosage volume is 100 μL. A total of TargetMol | Animal experiments 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify.
1 Enter information below:
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2 Enter the in vivo formulation:
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