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Atropine Oxide

Catalog No. T23763   CAS 4438-22-6
Synonyms: NSC 72861, NSC72861, NSC-72861

Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and pesticide poisonings as well as some types of slow heart rate.

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Atropine Oxide Chemical Structure
Atropine Oxide, CAS 4438-22-6
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Atropine Oxide is a derivative of Atropine. Atropine is a competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5. Atropine is a medication to treat certain types of nerve agents and pesticide poisonings as well as some types of slow heart rate.
Synonyms NSC 72861, NSC72861, NSC-72861
Molecular Weight 305.374
Formula C17H23NO4
CAS No. 4438-22-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Naghdi F, Gholamnezhad Z, Boskabady MH, Bakhshesh M. Muscarinic receptors, nitric oxide formation and cyclooxygenase pathway involved in tracheal smooth muscle relaxant effect of hydro-ethanolic extract of Lavandula angustifolia flowers. Biomed Pharmacother. 2018 Jun;102:1221-1228. doi: 10.1016/j.biopha.2018.04.004. Epub 2018 Apr 7. PubMed PMID: 29710541. 2. Oliveira Júnior RG, Ferraz CAA, Silva JC, de Andrade Teles RB, Silva MG, Diniz TC, Dos Santos US, de Souza AVV, Nunes CEP, Salvador MJ, Lorenzo VP, Quintans Júnior LJ, Almeida JRGDS. Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. J Ethnopharmacol. 2018 Apr 5;221:65-76. doi: 10.1016/j.jep.2018.04.009. [Epub ahead of print] PubMed PMID: 29627297. 3. Menezes PMN, Brito MC, de Paiva GO, Dos Santos CO, de Oliveira LM, de Araújo Ribeiro LA, de Lima JT, Lucchese AM, Silva FS. Relaxant effect of Lippia origanoides essential oil in guinea-pig trachea smooth muscle involves potassium channels and soluble guanylyl cyclase. J Ethnopharmacol. 2018 Mar 30;220:16-25. doi: 10.1016/j.jep.2018.03.040. [Epub ahead of print] PubMed PMID: 29609011. 4. Wei Y, Zhang CP, Guo S, Lu KH, Liu X, Yang Y, Liao ZH, Wu NB. [Effects of nitrogen form on accumulation of alkaloids and expression of relative genes in Atropa belladonna]. Zhongguo Zhong Yao Za Zhi. 2018 Jan;43(1):72-78. doi: 10.19540/j.cnki.cjcmm.2018.0003. Chinese. PubMed PMID: 29552814.

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Keywords

Atropine Oxide 4438-22-6 NSC 72861 NSC72861 NSC-72861 inhibitor inhibit

 

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