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Aplysistatin

Catalog No. T30099 CAS 62003-89-8

Aplysistatin is a bromosesquiterpene derived from sea mollusks.

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Aplysistatin, CAS 62003-89-8

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Aplysistatin is a bromosesquiterpene derived from sea mollusks.

Molecular Weight	329.23
Formula	C15H21BrO3
CAS No.	62003-89-8

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Couladouros EA, Vidali VP. Novel stereocontrolled approach to syn- and anti-oxepene-cyclogeranyl trans-fused polycyclic systems: asymmetric total synthesis of (-)-Aplysistatin, (+)-Palisadin A, (+)-Palisadin B, (+)-12-hydroxy-palisadin B, and the AB ring system of adociasulfate-2 and toxicol A. Chemistry. 2004 Aug 6;10(15):3822-35. PubMed PMID: 15281167. 2. Koshimura M, Utsukihara T, Kawamoto M, Saito M, Horiuchi CA, Kuniyoshi M. Biotransformation of bromosesquiterpenes by marine fungi. Phytochemistry. 2009 Dec;70(17-18):2023-6. doi: 10.1016/j.phytochem.2009.08.021. Epub 2009 Sep 21. PubMed PMID: 19772936. 3. Pettit GR, Herald CL, Allen MS, von Dreele RB, Vanell LD, Kao JP, Blake W. The isolation and structure of aplysistatin. J Am Chem Soc. 1977 Jan 5;99(1):262-3. PubMed PMID: 830682. 4. Su H, Yuan Z, Li J, Guo S, Han L, Zhu X, Shi D. [Studies on chemical constituents of Laurencia saitoi]. Zhongguo Zhong Yao Za Zhi. 2009 Apr;34(7):871-4. Chinese. PubMed PMID: 19623985.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Aplysistatin 62003-89-8 inhibitor inhibit

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