Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent.
Description | Amoxapine exerts its antidepressant effect by inhibiting the re-uptake of norepinephrine and, to a lesser degree, of serotonin, at adrenergic nerve endings and blocks the response of dopamine receptors to dopamine. Amoxapine is a tricyclic antidepressant of the dibenzoxazepine class. This drug is used to treat symptoms of depression and may cause tardive dyskinesia. Amoxapine also binds to alpha-adrenergic, histaminergic, and cholinergic receptors which accounts for many of the side effects seen with this agent. |
Targets&IC50 | GlyT1b:1 mM, GlyT2a:92 μM |
Synonyms | CL-67772, 阿莫沙平 |
Molecular Weight | 313.79 |
Formula | C17H16ClN3O |
CAS No. | 14028-44-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mg/mL (31.87 mM)
H2O: <1 mg/mL
Ethanol: <1 mg/mL
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Amoxapine 14028-44-5 神经科学 GlyT CL 67772 inhibit Inhibitor CL-67772 CL67772 inhibitor