CNS-Penetrant Compound Library

Catalog No. L5900

The blood–brain barrier (BBB) is a highly selective semipermeable border that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). In its neuroprotective role, the blood–brain barrier functions to hinder the delivery of many potentially important diagnostic and therapeutic agents to the brain. Overcoming the difficulty of delivering therapeutic agents to specific regions of the brain presents a major challenge to treatment of most brain disorders. Choosing the compounds that could penetrate BBB into the compound library targeting CNS is critical for CNS drug discovery. Based on the scientific literature, TargetMol collects 660 blood-brain barrier permeable compounds for research related to CNS-Penetrant and for the screening of drugs targeting central nervous system disorders. These compounds are suitable for high-throughput and high-content screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.