Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Aloisine A is a potent and selective CDK/GSK-3 inhibitor. IC50 data of Aloisine A: Cdk1/cyclin B (IC50: 150nM), Cdk2/cyclin A (IC50: 120nM), Cdk2/cyclin E (IC50: 400nM), Cdk5/p25 (IC50: 200nM), Cdk5/p35 (IC50: 160nM), GSK-3α (IC50: 500nM), GSK-3β (IC50: 650nM), JNK (IC50~3-10μM). |
Targets&IC50 | CDK5-p35:0.16 μM (IC50), ERK2:22 μM (IC50), CDK2-CyclinE:0.4 μM (IC50), JNK:3-10 μM (IC50), ERK1:18 μM (IC50), GSK-3α:1.5 μM (IC50), CDK2-CyclinA:0.12 μM (IC50), CDK1-CyclinB:0.15 μM (IC50), GSK-3β:0.5 μM (IC50) |
Molecular Weight | 267.33 |
Formula | C16H17N3O |
CAS No. | 496864-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Insoluble
DMSO: Soluble
You can also refer to dose conversion for different animals. More
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Aloisine A 496864-16-5 inhibitor inhibit