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Alatrofloxacin Mesylate

Catalog No. T29829 CAS 157605-25-9

Synonyms: UNII-2IXX802851, CP 116517, Alatrofloxacin mesylate (USAN), CP 116,517

Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin.

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Alatrofloxacin Mesylate Chemical Structure

Alatrofloxacin Mesylate, CAS 157605-25-9

Pack Size	Availability	Price/USD	Quantity
25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Alatrofloxacin Mesylate is the parental prodrug of broad-spectrum antibiotic trovafloxacin.

Synonyms	UNII-2IXX802851, CP 116517, Alatrofloxacin mesylate (USAN), CP 116,517
Molecular Weight	654.62
Formula	C27H29F3N6O8S
CAS No.	157605-25-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Mukherjee J. Post-approval translational research itself has diverse ethics. Am J Bioeth. 2010 Aug;10(8):43-4. doi: 10.1080/15265161.2010.496525. PubMed PMID: 20694908. 2. Hsiao CJ, Younis H, Boelsterli UA. Trovafloxacin, a fluoroquinolone antibiotic with hepatotoxic potential, causes mitochondrial peroxynitrite stress in a mouse model of underlying mitochondrial dysfunction. Chem Biol Interact. 2010 Oct 6;188(1):204-13. doi: 10.1016/j.cbi.2010.07.017. Epub 2010 Jul 23. PubMed PMID: 20655887. 3. Annas GJ. Globalized clinical trials and informed consent. N Engl J Med. 2009 May 14;360(20):2050-3. doi: 10.1056/NEJMp0901474. PubMed PMID: 19439740. 4. Ezeome ER, Simon C. Ethical problems in conducting research in acute epidemics: the Pfizer meningitis study in Nigeria as an illustration. Dev World Bioeth. 2010 Apr;10(1):1-10. doi: 10.1111/j.1471-8847.2008.00239.x. Epub 2008 Jul 28. PubMed PMID: 18665846.

Dose Conversion

You can also refer to dose conversion for different animals. More

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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Mass of a compound required to prepare a solution of known volume and concentration
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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Alatrofloxacin Mesylate 157605-25-9 UNII-2IXX802851 UNII-2IXX-802851 CP 116517 CP116517 USAN UNII-2IXX 802851 CP-116517 Alatrofloxacin mesylate (USAN) CP 116,517 inhibitor inhibit

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