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Acetylaranotin

Catalog No. T29597 CAS 20485-01-2

Synonyms: Antibiotic LL-S-88-A, LL-S-88-A

Acetylaranotin belongs to one structural subgroup of ETPs characterized by the presence of a seven-membered 4,5-dihydrooxepine ring.

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Acetylaranotin, CAS 20485-01-2

Pack Size	Availability	Price/USD
25 mg	10-14 weeks	$ 5,570.00
50 mg	10-14 weeks	$ 7,380.00
100 mg	10-14 weeks	$ 10,600.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Acetylaranotin belongs to one structural subgroup of ETPs characterized by the presence of a seven-membered 4,5-dihydrooxepine ring.

Synonyms	Antibiotic LL-S-88-A, LL-S-88-A
Molecular Weight	504.53
Formula	C22H20N2O8S2
CAS No.	20485-01-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Guo CJ, Yeh HH, Chiang YM, Sanchez JF, Chang SL, Bruno KS, Wang CC. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis. J Am Chem Soc. 2013 May 15;135(19):7205-13. doi: 10.1021/ja3123653. Epub 2013 May 1. PubMed PMID: 23586797; PubMed Central PMCID: PMC3695726. 2. Fujiwara H, Kurogi T, Okaya S, Okano K, Tokuyama H. Total synthesis of (-)-acetylaranotin. Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13062-5. doi: 10.1002/anie.201207307. Epub 2012 Nov 19. PubMed PMID: 23161829. 3. Belov DS, Ratmanova NK, Andreev IA, Kurkin AV. Synthesis of bicyclic proline derivatives by the aza-Cope-Mannich reaction: formal synthesis of (±)-acetylaranotin. Chemistry. 2015 Mar 2;21(10):4141-7. doi: 10.1002/chem.201405811. Epub 2015 Jan 28. PubMed PMID: 25631763. 4. Codelli JA, Puchlopek AL, Reisman SE. Enantioselective total synthesis of (-)-acetylaranotin, a dihydrooxepine epidithiodiketopiperazine. J Am Chem Soc. 2012 Feb 1;134(4):1930-3. doi: 10.1021/ja209354e. Epub 2011 Oct 28. PubMed PMID: 22023250; PubMed Central PMCID: PMC3271125.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Acetylaranotin 20485-01-2 Antibiotic LL-S-88-A LL-S-88-A inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.