Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 63.00 | |
5 mg | 35 days | $ 283.00 | |
10 mg | 35 days | $ 375.00 | |
25 mg | 35 days | $ 625.00 |
Description | AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5 |
Molecular Weight | 660.47 |
Formula | C26H33Cl2FN7O6P |
CAS No. | 722543-50-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL
DMSO: 1 mg/mL
You can also refer to dose conversion for different animals. More
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AZD 1152 (hydrochloride) 722543-50-2 AZD 1152 AZD1152 AZD-1152 inhibitor inhibit