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AZ9482

Catalog No. T22264 CAS 1825345-33-2

AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

AZ9482, CAS 1825345-33-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 52.00
5 mg	In stock	$ 133.00
10 mg	In stock	$ 215.00
25 mg	In stock	$ 409.00
50 mg	In stock	$ 595.00
100 mg	In stock	$ 866.00
1 mL * 10 mM (in DMSO)	In stock	$ 143.00

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Purity: 99.29%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	450.49
Formula	C26H22N6O2
CAS No.	1825345-33-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 125 mg/mL (277.48 mM), Sonication is recommended.

References and Literature

1. Howard R T , Hemsley P , Petteruti P , et al. Structure-Guided Design and In-Cell Target Profiling of a Cell-Active Target Engagement Probe for PARP Inhibitors[J]. ACS Chemical Biology, 2020, XXXX(XXX).

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Ovarian Cancer Compound Library Anti-Cardiovascular Disease Compound Library Epigenetics Compound Library Bioactive Compound Library Anti-Prostate Cancer Compound Library DNA Damage & Repair Compound Library Anti-Cancer Compound Library NO PAINS Compound Library Anti-Breast Cancer Compound Library

Related Products

Related compounds with same targets

K-756 Niraparib tosylate monohyrate 4beta-Hydroxywithanolide E Dehydrocorydaline nitrate Furanodiene IVHD-valtrate Veliparib Niraparib

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

AZ9482 1825345-33-2 Chromatin/Epigenetic DNA Damage/DNA Repair PARP breast inhibit poly ADP ribose polymerase AZ-9482 cancer AZ 9482 Inhibitor inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.