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ABT-719 HCl

Catalog No. T29531 CAS 162763-53-3

Synonyms: A-816719.1, A 816719.1, ABT-719, ABT719, ABT 719, ABT-719 hydrochloride

ABT-719 is a 2-pyridinone antimicrobial agent that is more effective against Enterococcus faecalis strains than ciprofloxacin and vancomycin, which showed resistance to ciprofloxacin and vancomycin covering a range of MIC.

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ABT-719 HCl, CAS 162763-53-3

Pack Size	Availability	Price/USD
25 mg	6-8 weeks	$ 1,670.00
50 mg	6-8 weeks	$ 2,180.00
100 mg	6-8 weeks	$ 2,800.00

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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	A-816719.1, A 816719.1, ABT-719, ABT719, ABT 719, ABT-719 hydrochloride
Molecular Weight	381.83
Formula	C18H21ClFN3O3
CAS No.	162763-53-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Jacoby GA, Corcoran MA, Hooper DC. Protective effect of Qnr on agents other than quinolones that target DNA gyrase. Antimicrob Agents Chemother. 2015 Nov;59(11):6689-95. doi: 10.1128/AAC.01292-15. Epub 2015 Aug 3. PubMed PMID: 26239981; PubMed Central PMCID: PMC4604369. 2. Ma Z, Chu DT, Cooper CS, Li Q, Fung AK, Wang S, Shen LL, Flamm RK, Nilius AM, Alder JD, Meulbroek JA, Or YS. Synthesis and antimicrobial activity of 4H-4-oxoquinolizine derivatives: consequences of structural modification at the C-8 position. J Med Chem. 1999 Oct 7;42(20):4202-13. PubMed PMID: 10514290. 3. Fung AK, Shen LL. The 2-pyridone antibacterial agents: 8-position modifications. Curr Pharm Des. 1999 Jul;5(7):515-43. Review. PubMed PMID: 10438895. 4. Saiki AY, Shen LL, Chen CM, Baranowski J, Lerner CG. DNA cleavage activities of Staphylococcus aureus gyrase and topoisomerase IV stimulated by quinolones and 2-pyridones. Antimicrob Agents Chemother. 1999 Jul;43(7):1574-7. PubMed PMID: 10390205; PubMed Central PMCID: PMC89326.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

ABT-719 HCl 162763-53-3 A-816719.1 A 816719.1 ABT 719 Hydrochloride ABT-719 ABT719 Hydrochloride ABT-719 Hydrochloride ABT719 ABT719 HCl ABT 719 ABT 719 HCl ABT-719 hydrochloride inhibitor inhibit

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