Powder: -20°C for 3 years | In solvent: -80°C for 1 year
A-80b is a synthesized pyridazino[4,5-b]indole derivate with potent and long-lasting antihypertensive activity. The decrease in diastolic pressure was greater than the decrease in systolic pressure and cardiac frequency was not modified significantly. A-80b shows dose-dependent inhibition of the Ca(2+)-induced contraction. Hypotensive and antihypertensive effect of A-80b possibly attributable to vasodilator activity via interference with Ca2+ influx and probably Ca2+ mobilization from intracellular stores.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 |
Description | A-80b is a synthesized pyridazino[4,5-b]indole derivate with potent and long-lasting antihypertensive activity. The decrease in diastolic pressure was greater than the decrease in systolic pressure and cardiac frequency was not modified significantly. A-80b shows dose-dependent inhibition of the Ca(2+)-induced contraction. Hypotensive and antihypertensive effect of A-80b possibly attributable to vasodilator activity via interference with Ca2+ influx and probably Ca2+ mobilization from intracellular stores. |
Synonyms | A80b, A-80b |
Molecular Weight | 307.35 |
Formula | C16H17N7 |
CAS No. | 135561-94-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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A 80b 135561-94-3 A80b A-80b inhibitor inhibit