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9(E),11(E),13(E)-Octadecatrienoic Acid

Catalog No. T36410 CAS 544-73-0

9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner.

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9(E),11(E),13(E)-Octadecatrienoic Acid Chemical Structure

9(E),11(E),13(E)-Octadecatrienoic Acid, CAS 544-73-0

Pack Size	Availability	Price/USD
1 mg	35 days	$ 143.00
5 mg	35 days	$ 623.00
10 mg	35 days	$ 1,090.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid. It reduces growth of Caco-2 colon cancer cells in a dose-dependent and time-dependent manner.
In vitro	In vitro, β-ESA induces DNA fragmentation and upregulation of pro-apoptotic Bax mRNA. β-ESA decreases protein expression of the apoptosis suppression factor Bcl-2 and induces apoptosis in T24 bladder cancer cells via production of reactive oxygen species. It also inhibits bacterial fatty acid dioxygenase with a Ki value of 49 nM in vitro.

Molecular Weight	278.436
Formula	C18H30O2
CAS No.	544-73-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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DMSO: 10 mg/mL

Ethanol: 20 mg/mL

DMF: 30 mg/mL

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Keywords

9(E),11(E),13(E)-Octadecatrienoic Acid 544-73-0 9(E),11(E),13(E) Octadecatrienoic Acid 9(E),11(E),13(E)Octadecatrienoic Acid 9,11,13Octadecatrienoic Acid inhibitor inhibit

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