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5,7-Dihydroxy-4-methylcoumarin

🥰Excellent
Catalog No. TJS0314Cas No. 2107-76-8
Alias Methyl-2H-Chromen-2-One, 4-Methyllimetol, 4-Methyl-5,7-Dihydroxycoumarin

5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-4-methylcoumarin shows inhibition of the cyclooxygenase pathway.

5,7-Dihydroxy-4-methylcoumarin

5,7-Dihydroxy-4-methylcoumarin

🥰Excellent
Purity: 99.43%
Catalog No. TJS0314Alias Methyl-2H-Chromen-2-One, 4-Methyllimetol, 4-Methyl-5,7-DihydroxycoumarinCas No. 2107-76-8
5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-4-methylcoumarin shows inhibition of the cyclooxygenase pathway.
Pack SizePriceAvailabilityQuantity
100 mg$42In Stock
1 mL x 10 mM (in DMSO)$46In Stock
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Purity:99.43%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) inhibits human neutrophil oxidative metabolism and elastase activity. 5,7-Dihydroxy-4-methylcoumarin has in vitro platelet antiaggregatory property. 5,7-Dihydroxy-4-methylcoumarin shows inhibition of the cyclooxygenase pathway.
SynonymsMethyl-2H-Chromen-2-One, 4-Methyllimetol, 4-Methyl-5,7-Dihydroxycoumarin
Chemical Properties
Molecular Weight192.17
FormulaC10H8O4
Cas No.2107-76-8
SmilesCc1cc(=O)oc2cc(O)cc(O)c12
Relative Density.1.456 g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 35 mg/mL (182.13 mM), Sonication is recommended.
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2037 mL26.0186 mL52.0373 mL260.1863 mL
5 mM1.0407 mL5.2037 mL10.4075 mL52.0373 mL
10 mM0.5204 mL2.6019 mL5.2037 mL26.0186 mL
20 mM0.2602 mL1.3009 mL2.6019 mL13.0093 mL
50 mM0.1041 mL0.5204 mL1.0407 mL5.2037 mL
100 mM0.0520 mL0.2602 mL0.5204 mL2.6019 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

InhibitorinhibitFungalBacterial5,7-Dihydroxy-4-methylcoumarin5,7Dihydroxy4methylcoumarin5,7 Dihydroxy 4 methylcoumarin
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