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48740 RP

Catalog No. T10159 CAS 93363-11-2

Synonyms: RP-48740, RP-55778, RP 55779, RP 55778

48740 RP (RP 55779) is an antagonist of platelet-activating factor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

48740 RP, CAS 93363-11-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 626.00
5 mg	In stock	$ 996.00
10 mg	In stock	$ 1,590.00
25 mg	In stock	$ 2,360.00
50 mg	In stock	$ 3,190.00
100 mg	In stock	$ 4,280.00
1 mL * 10 mM (in DMSO)	In stock	$ 995.00

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Purity: 99.4%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	48740 RP (RP 55779) is an antagonist of platelet-activating factor.
In vivo	48740 RP significantly reduces capillary permeability. 48740 RP increases the number of platelets at a time corresponding to 2 and 4 h after the exposure to lipopolysaccharide (LPS) and the number of eosinophils is also slightly increased. 48740 RP in combination with the LPS exposure increases the number of neutrophils by about half at 24 h[1].

Synonyms	RP-48740, RP-55778, RP 55779, RP 55778
Molecular Weight	245.3
Formula	C12H11N3OS
CAS No.	93363-11-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (224.22 mM)

References and Literature

1. Rylander R, et al. Modulation of pulmonary inflammation after endotoxin inhalation with a platelet-activating factor antagonist (48740 RP). Int Arch Allergy Appl Immunol. 1988;86(3):303-7.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

48740 RP 93363-11-2 GPCR/G Protein Others PAFR Platelet aggregation RP55778 RP-48740 RP 48740 RP-55779 RP48740 RP-55778 RP55779 RP 55779 RP 55778 inhibitor inhibit

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