keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 235.00 | |
5 mg | 35 days | $ 423.00 | |
10 mg | 35 days | $ 763.00 |
Description | 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency. |
Molecular Weight | 441.36 |
Formula | C16H18NaO11S |
CAS No. | 206443-06-3 |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL
PBS (pH 7.2): 10 mg/mL
DMF: 30 mg/mL
You can also refer to dose conversion for different animals. More
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4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) 206443-06-3 4Methylumbelliferyl βDGalactopyranoside6sulfate (sodium salt) 4 Methylumbelliferyl β D Galactopyranoside 6 sulfate (sodium salt) inhibitor inhibit