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2-Ethynyl Adenosine

Catalog No. T29347 CAS 99044-57-2

Synonyms: 2-Ethynyl-Ade, 2 Ethynyl Adenosine, 2-Ethynyl-Adenosine

2-Ethynyl Adenosine is an Adenosine derivative that is used to capture novel polyadenylated transcription and non-radiochemical reporter molecules of the protein AMPylation.

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2-Ethynyl Adenosine, CAS 99044-57-2

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Biological Description

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Description

2-Ethynyl Adenosine is an Adenosine derivative that is used to capture novel polyadenylated transcription and non-radiochemical reporter molecules of the protein AMPylation.

Synonyms	2-Ethynyl-Ade, 2 Ethynyl Adenosine, 2-Ethynyl-Adenosine
Molecular Weight	291.26
Formula	C12H13N5O4
CAS No.	99044-57-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Creech C, Kanaujia M, Causey CP. Synthesis and evaluation of 2-ethynyl-adenosine-5'-triphosphate as a chemical reporter for protein AMPylation. Org Biomol Chem. 2015 Aug 21;13(31):8550-5. doi: 10.1039/c5ob01081k. PubMed PMID: 26173047. 2. Tosh DK, Deflorian F, Phan K, Gao ZG, Wan TC, Gizewski E, Auchampach JA, Jacobson KA. Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions. J Med Chem. 2012 May 24;55(10):4847-60. doi: 10.1021/jm300396n. Epub 2012 May 16. PubMed PMID: 22559880; PubMed Central PMCID: PMC3371665. 3. Mathieu R, Baurand A, Schmitt M, Gachet C, Bourguignon JJ. Synthesis and biological activity of 2-alkylated deoxyadenosine bisphosphate derivatives as P2Y(1) receptor antagonists. Bioorg Med Chem. 2004 Apr 1;12(7):1769-79. PubMed PMID: 15028267.

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Keywords

2-Ethynyl Adenosine 99044-57-2 2-Ethynyl-Ade 2 Ethynyl Adenosine 2Ethynyl Adenosine 2-Ethynyl-Adenosine inhibitor inhibit

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