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17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

Catalog No. T37941 CAS 1138395-10-4

Synonyms: 17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.

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17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide Chemical Structure

17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide, CAS 1138395-10-4

Pack Size	Availability	Price/USD
1 mg	35 days	$ 183.00
5 mg	35 days	$ 793.00
10 mg	35 days	$ 1,430.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide
Molecular Weight	441.612
Formula	C27H39NO4
CAS No.	1138395-10-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMF: 25 mg/mL

PBS (pH 7.2): 0.25 mg/mL

Ethanol: 50 mg/mL

DMSO: 25 mg/mL

Acetonitrile: 3 mg/mL

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Keywords

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