Powder: -20°C for 3 years | In solvent: -80°C for 1 year
12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
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Description | 12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters. |
Molecular Weight | 369.33 |
Formula | C20H26Cl2O2 |
CAS No. | 65281-77-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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12,14-Dichlorodehydroabietic acid 65281-77-8 12,14 Dichlorodehydroabietic acid 12,14Dichlorodehydroabietic acid inhibitor inhibit