Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Dehydro-[10]-gingerdione inhibits IKKβ activity by targeting its activation loop, thereby preventing IKKβ-mediated phosphorylation of IκBα in macrophages stimulated by agonists. Furthermore, this compound suppresses LPS-induced NF-κB transcriptional activity, highlighting its potential in research related to NF-κB-associated inflammation and autoimmune disorders [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | 1-Dehydro-[10]-gingerdione inhibits IKKβ activity by targeting its activation loop, thereby preventing IKKβ-mediated phosphorylation of IκBα in macrophages stimulated by agonists. Furthermore, this compound suppresses LPS-induced NF-κB transcriptional activity, highlighting its potential in research related to NF-κB-associated inflammation and autoimmune disorders [1]. |
Molecular Weight | 346.46 |
Formula | C21H30O4 |
CAS No. | 136826-50-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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1-Dehydro-[10]-gingerdione 136826-50-1 inhibitor inhibit