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(S)-3,4-DCPG

Catalog No. T23288 CAS 201730-11-2

Synonyms: (S)-3,4-Dicarboxyphenylglycine

(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).

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(S)-3,4-DCPG, CAS 201730-11-2

Pack Size	Availability	Price/USD
1 mg	4-5 weeks	$ 78.00
5 mg	4-5 weeks	$ 297.00
10 mg	4-5 weeks	$ 498.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).
Targets&IC50	mGluR8a (human):31 nM (EC50)
In vitro	(S)-3,4-DCPG inhibited forskolin-stimulated cAMP formation in cells expressing mGlu8 with an EC50 value of 0.031 µM[1].

Synonyms	(S)-3,4-Dicarboxyphenylglycine
Molecular Weight	239.18
Formula	C10H9NO6
CAS No.	201730-11-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Soluble

References and Literature

1. Thomas NK, et al. (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord. Neuropharmacology. 2001 Mar;40(3):311-8.

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Keywords

(S)-3,4-DCPG 201730-11-2 Neuroscience GluR (S)-3,4-Dicarboxyphenylglycine 3,4-DCPG 3,4-Dicarboxyphenylglycine inhibitor inhibit

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