Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact.
Description | ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employed to deter mosquito contact. |
In vitro | Studies on hepatoma cells demonstrate that treatment with ω-Hydroxy-DEET (DHMB; at concentrations ranging from 0.1 to 10 μg/mL for durations of 48 to 72 hours) leads to decreased cellular proliferation [1]. |
In vivo | Following both intravenous and topical administration of DEET in rats, the metabolite ω-Hydroxy-DEET (DHMB) showed extensive distribution, with ω-Hydroxy-DEET emerging as DEET's principal metabolite. Notably, repeated daily topical applications over a 30-day period resulted in elevated ω-Hydroxy-DEET concentrations in the liver[1]. |
Molecular Weight | 207.27 |
Formula | C12H17NO2 |
CAS No. | 72236-22-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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ω-Hydroxy-DEET 72236-22-7 ω Hydroxy DEET omega-Hydroxy-DEET w-Hydroxy-DEET ωHydroxyDEET inhibitor inhibit