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β-Damascone

Name: β-Damascone
Brand: TargetMol
SKU: TN6742
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN6742Cas No. 23726-91-2

β-Damascone are a series of closely related chemical compounds that are components of a variety of essential oils. The damascones belong to a family of chemicals known as rose ketones, which also includes damascenones and ionones. beta-Damascone is a contributor to the aroma of roses, despite its relatively low concentration, and is an important fragrance chemical used in perfumery.

β-Damascone

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Purity: 97.50%

Catalog No. TN6742Cas No. 23726-91-2

Pack Size	Price	USA Warehouse	Global Warehouse
50 mg	$30	-	In Stock
100 mg	$40	-	In Stock
500 mg	$106	-	In Stock
1 g	$156	-	In Stock
1 mL x 10 mM (in DMSO)	$44	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.50%

Appearance:Liquid

Color:Transparent

Resource Download

COA HNMR HPLC

Product Introduction

β-Damascone AI Summary

β-Damascone shows bioactivity as an inhibitor of Acyl-CoA: Retinol Acyltransferase (ARAT) and Lecithin: Retinol Acyltransferase (LRAT) enzymes in bovine RPE microsomes. At a concentration of 10 μM, it inhibits ARAT by 45.0% and LRAT by 52.0%. At a higher concentration of 100 μM, it demonstrates stronger inhibition, with 84.0% inhibition of ARAT and 92.0% inhibition of LRAT. These findings suggest that β-Damascone has potential as a regulator of retinol metabolism pathways..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Chemical Properties

Molecular Weight	192.3
Formula	C₁₃H₂₀O
Cas No.	23726-91-2
Smiles	C(/C=C/C)(=O)C=1C(C)(C)CCCC1C
Relative Density.	0.936. Temperature:20 °C.

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (286.01 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (10.4 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.2002 mL	26.0010 mL	52.0021 mL	260.0104 mL
5 mM	1.0400 mL	5.2002 mL	10.4004 mL	52.0021 mL
10 mM	0.5200 mL	2.6001 mL	5.2002 mL	26.0010 mL
20 mM	0.2600 mL	1.3001 mL	2.6001 mL	13.0005 mL
50 mM	0.1040 mL	0.5200 mL	1.0400 mL	5.2002 mL
100 mM	0.0520 mL	0.2600 mL	0.5200 mL	2.6001 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc