Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 293.00 | |
50 μg | 35 days | $ 555.00 | |
100 μg | 35 days | $ 987.00 | |
250 μg | 35 days | $ 2,320.00 |
Description | (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites. |
Molecular Weight | 318.457 |
Formula | C20H30O3 |
CAS No. | 83952-40-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 0.8 mg/mL
DMSO: Miscible
0.1 M Na2CO3: 2 mg/mL
Ethanol: Miscible
DMF: Miscible
You can also refer to dose conversion for different animals. More
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(±)5-HEPE 83952-40-3 (±)5 HEPE (±)5HEPE 5-HEPE inhibitor inhibit