Ahistonemodificationis a covalent post-translational enzymatic modification to histone proteins which includesmethylation,phosphorylation,acetylation, ubiquitylation, and sumoylation.Histone modification impactsgene expressionbyaltering chromatin structureor recruiting histone modifiers.Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation,chromosomepackaging, and DNA damage/repair.Thus, quantitative detection of various histone modifications would provide useful information for a better understanding ofepigeneticregulation of cellular processes and the development of histone modifying enzyme-targeted drugs.
The TargetMol’sHistone Modification Research Compound Library, a unique collection of 152 histone modification related compounds, can be used for research in histone modification and related drug screening.
|100 μL * 10 mM (in DMSO)||USD 2432.00|
|250 μL * 10 mM (in DMSO)||USD 4408.00|
|1 mg||USD 4408.00|
The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.