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Home > Screening Libraries > Histone Modification Research Compound Library

Histone Modification Research Compound Library

Catalog No. L3500

Ahistonemodificationis a covalent post-translational enzymatic modification to histone proteins which includesmethylation,phosphorylation,acetylation, ubiquitylation, and sumoylation.Histone modification impactsgene expressionbyaltering chromatin structureor recruiting histone modifiers.Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation,chromosomepackaging, and DNA damage/repair.Thus, quantitative detection of various histone modifications would provide useful information for a better understanding ofepigeneticregulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol’sHistone Modification Research Compound Library, a unique collection of 152 histone modification related compounds, can be used for research in histone modification and related drug screening.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 2432.00
250 μL * 10 mM (in DMSO) USD 4408.00
1 mg USD 4408.00

Product Description

  • A unique collection of 152 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Safety and effectiveness of the small molecules have been demonstrated through preclinical and clinical research;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with blue ice; Stable for One year as powder, 6 months at - 20 ° C in DMSO or 12months at -80 ° C in DMSO

Library Composition

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