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Histone Modification Research Compound Library

Catalog No. L3500

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol’s Histone Modification Research Compound Library, a unique collection of 152 histone modification related compounds, can be used for research in histone modification and related drug screening.

Pack Size Price
100 μL * 10 mM (in DMSO) USD 2432.00
250 μL * 10 mM (in DMSO) USD 4408.00
1 mg USD 4408.00

Product Description

  • A unique collection of 152 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

The compound library can be highly customized. You can select compounds, quantities, format (dry/solid or DMSO), plate map, and concentration to meet your specific requirement. Please check our Compound Library Instructions for more information.

Packaging and Storage

  • Powder or pre-dissolved DMSO solutions in 96 well plate with optional 2D barcode
  • Shipped with dry ice.

Library Composition

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