Compound Libraries Alkaloids natural compound library

Alkaloids natural compound library

Catalog No. L6110
  Library Compound List   Excel SDF

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, and mainly produced by plant. A large amount of research have found that alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. As research in alkaloids advances, alkaloids would play an important and visible role in modern drug development and provide a continuing source of novel drug leads.

TargetMol’s Alkaloids Natural Compound Library carefully collects 317 alkaloids derived from plants, including Aconite, Periwinkle, Camptotheca acuminate, Belladonna, Coptis chinensis, etc. They have anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects. For example, vinca alkaloids obtained from Madagascar periwinkle plant are important for being cancer fighters and are the second-most-used class of cancer drugs and will stay among the original caner therapies. Lycorine, one of the main alkaloids of the Amaryllidaceae family, was found to be responsible for the pronounced antiviral and antibacterial activity of the crude extracts from the roots and leaves of Clivia miniata Regel. Tetrahydropalmatine, an isoquinoline alkaloid that is considered the active ingredient of Corydalis yanhusuo, has significant analgesic effects.

Pack Size Price/USD
100 μL * 10 mM (in DMSO) 5700.00
250 μL * 10 mM (in DMSO) 9510.00
1 mg 9510.00
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Product Description

  • A unique collection of 317 natural alkaloids can be used for high throughput and high content screening;
  • Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
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Library Composition

AChR (31)
Topoisomerase (14)
P450 (10)
5-HT Receptor (10)
Sodium Channel (10)
NF-κB (9)
Potassium Channel (8)
Adrenergic Receptor (8)
Autophagy (7)
Microtubule Associated (7)
Antioxidant (6)
Antibacterial (5)
Antifection (5)
Calcium Channel (5)
Dopamine Receptor (5)
Antifungal (4)
Antibiotic (4)
p38 MAPK (4)
TRP/TRPV Channel (4)
ROS (3)
TNF (3)
NOS (3)
IDO (3)
PDE (3)
Antiviral (3)
Caspase (3)
Chloride channel (3)
ERK (3)
GABA Receptor (3)
HCV Protease (2)
FAK (2)
EGFR (2)
Endogenous Metabolite (2)
COX (2)
CaMK (2)
Apoptosis (2)
BACE (2)
BCL (2)
Bcr-Abl (2)
Beta Amyloid (2)
AMPK (2)
P-gp (2)
PKC (2)
Prostaglandin Receptor (2)
STAT (2)
IL Receptor (2)
MAO (2)
Hedgehog/Smoothened (2)
Nucleoside Antimetabolite/Analog (2)
Opioid Receptor (1)
MMP (1)
MRP (1)
NO Synthase (1)
HIF (1)
Histamine Receptor (1)
HSP (1)
MAPK (1)
MEK (1)
TGF-beta/Smad (1)
TLR (1)
PPAR (1)
Platelet aggregation (1)
p53 (1)
Parasite (1)
PARP (1)
Androgen Receptor (1)
Akt (1)
ATPase (1)
DYRK (1)
Dehydrogenase (1)
DNA gyrase (1)
DNA/RNA Synthesis (1)
HDAC (1)
GluR (1)
S1P Receptor (1)
Sirtuin (1)