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L162389

🥰Excellent
Catalog No. T11808Cas No. 169281-53-2
Alias L-162389, L 162389

L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.

L162389

L162389

🥰Excellent
Purity: 99.68%
Catalog No. T11808Alias L-162389, L 162389Cas No. 169281-53-2
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Pack SizePriceAvailabilityQuantity
1 mg$333In Stock
5 mg$790In Stock
10 mg$1,120In Stock
25 mg$1,670In Stock
50 mg$2,180In Stock
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Purity:99.68%
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Product Introduction

Bioactivity
Description
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Targets&IC50
AT1 receptor:28 nM (Ki)
In vitro
METHODS: To determine the characteristics of the non-peptide angiotensin AT1 ligand L162389, a series of affinity assay studies were conducted.
RESULTS: L162389 also stimulated phosphatidylinositol turnover, although only a minor fraction of the angiotensin response, acting as an angiotensin antagonist with an IC50 of 105 nM [1].
AliasL-162389, L 162389
Chemical Properties
Molecular Weight562.72
FormulaC31H38N4O4S
Cas No.169281-53-2
SmilesO=C(OCCCC)NS(=O)(=O)C=1C=CC(=CC1C2=CC=C(C=C2)CN3C4=NC(=CC(=C4N=C3CC)C)C)CCC
Relative Density.1.21 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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