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cis-(Z)-Flupentixol dihydrochloride

Catalog No. T2564 CAS 51529-01-2

Synonyms: Flupenthixol dihydrochloride, Emergil

Flupenthixol dihydrochloride is a dopamine receptor antagonist.

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cis-(Z)-Flupentixol dihydrochloride, CAS 51529-01-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Flupenthixol dihydrochloride is a dopamine receptor antagonist.
Targets&IC50	D 2 Receptor:0.38 nM (Ki), 5-HT 2A Receptor:7 nM (Ki)

Synonyms	Flupenthixol dihydrochloride, Emergil
Molecular Weight	507.44
Formula	C23H27Cl2F3N2OS
CAS No.	51529-01-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Dwivedi VS, et al. Curr Med Res Opin. 1990;12(3):191-7.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

cis-(Z)-Flupentixol dihydrochloride 51529-01-2 GPCR/G Protein Neuroscience 5-HT Receptor Dopamine Receptor 5-hydroxytryptamine Receptor Flupenthixol dihydrochloride inhibit cis (Z) Flupentixol dihydrochloride Serotonin Receptor cis(Z)Flupentixol dihydrochloride Emergil Inhibitor inhibitor

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