Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is an E3 ligase ligand-linker conjugate which is designed using Thalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is synthesized specifically for utilization in PROTAC technology.
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Description | Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3) is an E3 ligase ligand-linker conjugate which is designed using Thalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is synthesized specifically for utilization in PROTAC technology. |
In vitro | Thalidomide-O-amido-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 3), consisting of a Degron (E3 ubiquitin ligase) and a linker, is utilized in PROTAC technology to facilitate the degradation of target proteins, including BRD4, BRD2, and BRD3, by binding to the targeting ligand[1]. |
Synonyms | Cereblon Ligand-Linker Conjugates 3, E3 Ligase Ligand-Linker Conjugates 14 |
Molecular Weight | 506.51 |
Formula | C23H30N4O9 |
CAS No. | 1957236-20-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-O-amido-PEG3-C2-NH2 1957236-20-2 Others Cereblon Ligand-Linker Conjugates 3 Thalidomide-O-amido-PEG-3-C2-NH2 E3 Ligase Ligand-Linker Conjugates 14 ThalidomideOamidoPEG3C2NH2 Thalidomide O amido PEG3 C2 NH2 inhibitor inhibit