Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to CD36 receptors on the surface of microglia.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 32.00 | |
5 mg | In stock | $ 66.00 | |
10 mg | In stock | $ 119.00 | |
25 mg | In stock | $ 197.00 | |
50 mg | In stock | $ 315.00 | |
100 mg | In stock | $ 497.00 | |
200 mg | In stock | $ 638.00 | |
500 mg | In stock | $ 987.00 |
Description | Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to CD36 receptors on the surface of microglia. |
In vitro | Sulfosuccinimidyl oleate (50 μM, 24 hours) co-treatment significantly reduces the LPS+IFNγ-induced expression of NOS2 and COX-2 in BV2 cells. Western blot analysis reveals a significant LPS/IFNγ-induced upregulation in the phosphorylated form of the p38, which is prevented by co-treatment with Sulfosuccinimidyl oleate (50 μM, 24 hours)[1]. |
In vivo | In male BALB/cABom mice with pMCAo model, Sulfosuccinimidyl oleate (50 mg/kg; administered once by single oral gavage) significantly reduces the cortical ischemic infarct size compared to vehicle-treated controls. In addition, Sulfosuccinimidyl oleate(50 mg/kg) is suitable to see a beneficial effect after stroke[1]. |
Synonyms | Sulfo-N-succinimidyl oleate sodium |
Molecular Weight | 481.58 |
Formula | C22H36NNaO7S |
CAS No. | 1212012-37-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (124.59 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Sulfosuccinimidyl oleate sodium 1212012-37-7 Others Sulfo-N-succinimidyl oleate sodium inhibitor inhibit