Powder: -20°C for 3 years | In solvent: -80°C for 1 year
STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 41.00 | |
5 mg | In stock | $ 67.00 | |
10 mg | In stock | $ 117.00 | |
25 mg | In stock | $ 255.00 | |
50 mg | In stock | $ 452.00 | |
100 mg | In stock | $ 665.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 74.00 |
Description | STK16-IN-1 is an inhibitor of STK16 kinase (IC50: 295 nM). |
Targets&IC50 | STK16:295 nM |
In vitro | STK16-IN-1 inhibits mTOR kinase (IC50: 5.56 μM). STK16-IN-1 shows potent inhibitory activity against STK16 kinase (IC50=0.295 μM) with excellent selective across the kinome as assessed using the KinomeScanTM profiling assay. STK16-IN-1 treatment causes a reduction in cell number and accumulation of binucleated cells, which can be recapitulated by RNAi knockdown of STK16 in MCF-7 cells. Co-treatment of STK16-IN-1 with chemotherapeutics such as cisplatin, doxorubicin, colchicine and paclitaxel results in a slight potentiation of the anti-proliferative effects of the chemotherapeutics. STK16-IN-1 provides a useful tool compound for further elucidating the biological functions of STK16) [1]. |
Molecular Weight | 293.3 |
Formula | C17H12FN3O |
CAS No. | 1223001-53-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 15 mg/mL (51.14 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. More
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STK16-IN-1 1223001-53-3 Others STK16IN1 STK-16-IN-1 Inhibitor STK16 IN 1 inhibit inhibitor