Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 48.00 | |
5 mg | In stock | $ 79.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 272.00 | |
50 mg | In stock | $ 446.00 | |
100 mg | In stock | $ 658.00 | |
500 mg | In stock | $ 1,380.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 95.00 |
Description | RAF709 is a novel Raf kinase inhibitor with IC50s of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively. |
Targets&IC50 | B-Raf:1.8 nM, C-Raf:0.5 nM |
In vitro | The invention provides compounds (e.g., RAF709) that inhibit Raf kinases, and are accordingly useful for treating certain disorders associated with excessive Raf kinase activity, including cell proliferation disorders such as cancers[1]. |
Molecular Weight | 542.55 |
Formula | C28H29F3N4O4 |
CAS No. | 1628838-42-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 91 mg/mL(167.8 mM)
You can also refer to dose conversion for different animals. More
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RAF709 1628838-42-5 MAPK Raf Inhibitor inhibit RAF-709 Raf kinases RAF 709 inhibitor