Shopping Cart
- Remove All
Your shopping cart is currently empty
NNC-0640
🥰Excellent
Catalog No. T7364Cas No. 307986-98-7
NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
NNC-0640
🥰Excellent
Purity: 97.04%
Catalog No. T7364Cas No. 307986-98-7
NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $41 | In Stock | |
| 2 mg | $59 | In Stock | |
| 5 mg | $97 | In Stock | |
| 10 mg | $172 | In Stock | |
| 25 mg | $313 | In Stock | |
| 50 mg | $478 | In Stock | |
| 100 mg | $689 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $97 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "NNC-0640"
PF-06882961
Danuglipron
T124312230198-02-2
PF-06882961 is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
- $42
Size
QTY
PF-06882961 Tris
UNII-2HJV78O0SS
T88762230198-03-3
PF-06882961 Tris (UNII-2HJV78O0SS) is an orally bioavailable glucagon-like peptide-1 receptor (GLP-1R) agonist.
- $133
Size
QTY
Tirzepatide Acetate(2023788-19-2 free base)
TP1111L
Tirzepatide (LY3298176) Acetate (2023788-19-2 free base) is a new molecule that can control blood glucose levels by combining dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors.[3]
- $358
Size
QTY
(S, R)-LSN 3318839
(S, R)-LSN 3318839(Isomer-2764704-18-7)
T63166L2765539-92-0In house
(S,R)-LSN 3318839 enhances GLP-1R, shows strong blood sugar lowering in animals, works with sitagliptin.
- $195
Size
QTY
Glucagon (1-29), bovine, human, porcine hydrochloride
Glucagon hydrochloride
T15389L28270-04-4
Glucagon (1-29), bovine, human, porcine hydrochloride (Porcine glucagon hydrochloride) is a peptide hormone produced by pancreatic α-cells that activates HNF4α, increases HNF4α phosphorylation, and stimulates gluconeogenesis.
- $79
Size
QTY
GLP-1R modulator L7-028
GLP-1R modulator L7-028
T402792648317-95-5
GLP-1R modulator L7-028 is a variant that enhances affinity for GLP-1 and (cAMP) signaling.
- $58
Size
QTY
Bay 55-9837 acetate
TP2071L
Bay 55-9837 acetate is a potent and highly selective VPAC2 agonist(Kd = 0.65 nM) and can be used in type 2 diabetes studies.
- $323
Size
QTY
6α-Methylprednisolone 21-hemisuccinate sodium salt
Metypresol, Methylprodnisolone Sodium Succinate, Methylprednisolone sodium succinate, Corticel, Asmacortone, 6-Methylprednisolone succinate sodium
T02942375-03-3
6α-Methylprednisolone 21-hemisuccinate sodium salt (Asmacortone), a water-soluble ester, is used for allergic, cardiac, and hypoxic emergencies.
- $39
Size
QTY
Orforglipron
LY3502970, GLP-1 receptor agonist 1
T114082212020-52-3
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
- $256
Size
QTY
Adomeglivant
LY2409021
T141301488363-78-5
Adomeglivant (LY2409021) is a potent and selective glucagon receptor antagonist. Which is used in clinical trial for type 2 diabetes mellitus.
- $118
Size
QTY
NNC 92-1687
NNC92-1687, NNC-92-1687
T2818222903-37-3In house
NNC 92-1687 is a selective glucagon receptor antagonist that can be used to study type 2 diabetes.
- $396
Size
QTY
LSN3318839
LSN-3318839, LSN 3318839
T631662764704-18-7In house
LSN3318839 is a potent and orally available glucagon-like peptide-1 receptor (GLP-1R) modulator.LSN3318839 enhances GLP-1R G-protein-coupled signaling and can be used to lower blood glucose.
- $213
Size
QTY
Select Batch
Purity:97.04%
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | NNC-0640 is a negative allosteric modulator of Human Glucagon Receptor with an IC50 of 69.2 nM. |
| Targets&IC50 | Glucagon receptor (human):69.2 nM |
| Molecular Weight | 573.67 |
| Formula | C29H31N7O4S |
| Cas No. | 307986-98-7 |
| Smiles | CS(=O)(=O)c1cccc(NC(=O)N(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2ccc(cc2)C2CCCCC2)c1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
| Solubility Information | DMSO: 25 mg/mL (43.58 mM), Sonication is recommended.  | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||
Sci Citations
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy NNC-0640 | purchase NNC-0640 | NNC-0640 cost | order NNC-0640 | NNC-0640 chemical structure | NNC-0640 formula | NNC-0640 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.