Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast malignancies. It exhibits antimicrobial and anti-proliferative activities.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 35 days | $ 1,420.00 |
Description | Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast malignancies. It exhibits antimicrobial and anti-proliferative activities. |
In vitro | Meleagrin induces a dose-dependent inhibition of HGF-induced cell migration, and invasion of breast cancer cell lines. Meleagrin suppresses the growth of the human breast cancer cell lines MDA-MB-231, MDA-468, BT-474, SK BR-3, MCF7 and MCF7-dox [3]. |
In vivo | In an orthotopic athymic nude mice model, Meleagrin effectively inhibits the invasive triple-negative breast tumor cell growth[3]. |
Molecular Weight | 433.46 |
Formula | C23H23N5O4 |
CAS No. | 71751-77-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Meleagrin 71751-77-4 Others inhibitor inhibit